Prognostic relevance of rosette-like features in osteosarcoma

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Prognostic relevance of rosette-like features in osteosarcoma.

AIMS To clarify the prognostic relevance of rosette-like features and other clinicopathological and immunohistochemical variables in patients with osteosarcoma. METHODS Clinicopathological and immunohistochemical variables were analysed in 131 patients with non-metastatic high grade conventional osteosarcoma, with particular attention to the prognostic impact of rosette-like features. RESUL...

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Prognostic relevance of increased angiogenesis in osteosarcoma.

9022 Background: Osteosarcoma, the most frequent primary malignant bone tumor is a chemotherapy-sensitive tumor with survival rates reaching 50 to 80 %. Several reports have demonstrated that neovascularization assessed by intratumoral microvessel density (MVD) correlates with clinicopathological factors and the patients' prognosis in a variety of tumors. However, the role of angiogenesis in os...

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[Clinical features in osteosarcoma and prognostic implications].

OBJECTIVE To identify the clinical features in osteosarcoma and to investigate their influence on the prognosis of children and adolescents presenting this disease. MATERIAL AND METHODS The records of children and adolescents with osteosarcoma treated by the Bone Tumors Group of the state of Rio Grande do Sul, Brazil, between January 1992 and December 2001 were reviewed. RESULTS Fifty conse...

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prognostic importance of the pathologic fracture and surgical options in osteosarcoma: a retrospective clinical study

Background & Aims: Osteosarcoma is one of the most prevalent malignant bone tumors . This study is designed to assess the prognostic effect of pathologic fracture and treatment options on survival of patients with osteosarcoma. Materials & Methods: In this study, prognosis of 106 patients with limb osteosarcoma, which were treated at three  hospitals in Tehran from April to August 2012 ...

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Rosette-forming epithelioid osteosarcoma in childhood: a case report

Osteosarcoma with epithelioid appearance and a rosette-like configuration is a rare, recently reported variation in osteogenic sarcoma, which is thought to be associated with a poor prognosis. We report an unusual pediatric case of rosette-forming epithelioid osteosarcoma with poor response to neoadjuvant chemotherapy and repeated local recurrence following surgical resection. A 6-year-old boy ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2003

ISSN: 0021-9746

DOI: 10.1136/jcp.56.11.831